Epidemiological Analysis of Water Contaminants and Their Correlation with Leukemia and Non-Hodgkin Lymphoma Incidence in Florida

Introduction

This study investigates the incidence of leukemia and non-Hodgkin lymphoma (NHL) in relation to various water contaminants, including arsenic, across different counties in Florida. Arsenic, a known carcinogen, and other chemicals, such as haloacetic acid, radium, chromium, and trihalomethanes, have been detected in multiple water sources, prompting public health concerns^1-4.

Methods

A meticulous and comprehensive epidemiological analysis was conducted using data from National Institute of Health database and the Environmental Working Group's tap water contaminant database. The study population included individuals residing in areas with documented contamination compared to those in regions with low or non-detectable levels. Correlation coefficients were calculated to assess the relationship between contaminant exposure and cancer incidence, ensuring the thoroughness and reliability of the findings.

Results

Statistical analysis revealed a moderately strong correlation between arsenic exposure and the incidence of leukemia (correlation coefficient = 0.47) and NHL (correlation coefficient = 0.21). Similarly, chromium exposure showed a moderately strong correlation with leukemia (correlation coefficient = 0.42) and a weaker correlation with NHL (correlation coefficient = 0.052). In contrast, haloacetic acid and trihalomethanes were negatively correlated with both leukemia and NHL, while radium showed a minimal correlation with leukemia and a weak positive correlation with NHL.

Conclusion

These results underscore the potential impact of continued water quality monitoring and mitigation strategies in reducing exposure to these contaminants. While the study found weak to moderately strong correlations, it highlights the significant role of environmental factors in cancer prevention efforts. Further research is recommended to explore the biological mechanisms underlying contaminant-induced carcinogenesis and to develop effective public health interventions, emphasizing the potential impact of this research on public health.

No relevant conflicts of interest to declare.